Meet Dr. Marc Abreu, pioneer of the BTT method
Professional Profile
Dr. Marc Abreu is a renowned physician and surgeon with an academic and scientific career of international scope. He graduated from the Escola Paulista de Medicina at the Federal University of São Paulo (Unifesp), in Brazil, where he also completed his medical residency and earned his specialization in Ophthalmology. Dr. Abreu expanded his education at some of the most prestigious institutions in the world, including the Schools of Medicine at Indiana University, the University of Pittsburgh, Harvard University, and Yale University in the United States. Throughout his career, he has served as a faculty member at both Harvard and Yale Medical Schools, where he also co-directed the Interdisciplinary Research Group on BTT (Brain Thermal Tunnel).
Innovation and Scientific Contributions
His contribution to science is marked by the discovery of the Brain Thermal Tunnel – a biological and thermophysical breakthrough that, for the first time, enabled the accurate, continuous, and non-invasive monitoring of human brain temperature.
Based on this revolutionary discovery, Dr. Abreu developed and patented the BTT technology and the Abreu BTT 700 System, cleared by the FDA (Food and Drug Administration, USA), which is now used as a crucial tool in the diagnosis and monitoring of various neurodegenerative and oncological diseases.
Internationally recognized, Dr. Marc Abreu holds over 116 patents registered in 60 countries, including Brazil and the United States, and has published more than 30 works, including scientific articles, preprints, and presentations at prestigious medical conferences. His first scientific article was published in 1985, early on demonstrating his dedication to health innovation.
Innovation and Scientific Contributions
Pioneering Work in Cerebral Thermodynamics
As Medical Director of the BTT Medical Institute, Dr. Abreu leads one of the world’s most advanced centers for treatments based on cerebral thermodynamics using BTT technology. He offers new therapeutic possibilities for patients facing complex conditions such as Alzheimer’s, Parkinson’s, and cancer.
Scientific articles and publications
Application of the pupil cycle time test in neurophthalmologic patients
Paulista School of Medicine, Federal University of São Paulo (UNIFESP)
Diode laser-pumped, frequency-doubled neodymium: YAG laser peripheral iridotomy
Effects of short term increase of intraocular pressure on optic disc cupping
Topical verapamil and episcleral venous pressure
Total Reversal of ALS Confirmed by EMG Normalization, Structural Reconstitution, and Neuromuscular–Molecular Restoration Achieved Through Computerized Brain-Guided Reengineering of the 1927 Nobel Prize Fever Therapy: A Case Report
BTT Medical Institute
Effect of topical anti-inflammatory treatment on the long-term outcome of laser trabeculoplasty. Fluorometholone-Laser Trabeculoplasty Study Group
Yale Physician Designs First Self-Testing Device for Glaucoma
An at-home test for glaucoma
Scientist invents device for at-home testing of glaucoma
Complete remission of stage IV prostate cancer by new non-invasive brain temperature-titrated brain-body hyperthermia
BTT Medical Institute
Discovery reveals new way to monitor body temperature
Yale Researcher Discovers "Brain Temperature Tunnel" That For The First Time Allows External Continuous Measurement of Brain Temperature
Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy
Previously unseen brain-eyelid thermal tunnel reveals biological waveguide and transorbital thermophysical pathway to the brain
Biophysical Basis of Thermometry Limitations to Control COVID-19 are Overcome at Transmissive Skin Overlying Brain-eyelid Thermal Tunnels
Brain thermal kinetics at brain-eyelid thermal tunnels overcoming COVID-19 thermometry limitations for automated asymptomatic infection detection in concert with physical and biological principles
Brain/core Discordance due to Neuronal Activity Identified by Noninvasive Brain Temperature Measurement via Brain-eyelid Thermal Tunnels
Previously unseen brain-eyelid thermal tunnel reveals biological waveguide and transorbital thermophysical pathway to the brain
Biophysical Basis of Thermometry Limitations to Control COVID-19 are Overcome at Transmissive Skin Overlying Brain-eyelid Thermal Tunnels
Brain thermal kinetics at brain-eyelid thermal tunnels overcoming COVID-19 thermometry limitations for automated asymptomatic infection detection in concert with physical and biological principles
Brain/core Discordance due to Neuronal Activity Identified by Noninvasive Brain Temperature Measurement via Brain-eyelid Thermal Tunnels
Noninvasive Assessment of Intracranial Temperature Via the Medial Canthal-Brain Temperature Tunnel
Noninvasive Surface Monitoring of Core Temperature Via a Medial Canthal Brain Temperature Tunnel
Noninvasive Core Temperature Monitoring during Cardiopulmonary Bypass Via a Brain Temperature Tunnel
Infrared Thermographic Analysis of Temperature on the Face, Forehead, Neck, and SuperoMedial Orbit
Noninvasive Documentation of Delayed Brain Cooling during Deliberate Hypothermia
Consistency of Brain Temperature Tunnel Measurements in Different Environmental Temperature
Anatomy of Skin Sites Contribute to Their Suitability or Lack Thereof for Temperature Monitoring
Temperature Can Be Much More Than a Dichotomous Variable
Detection of Brain Cooling during Craniotomy with a Surface Temperature Monitor
Noninvasive Monitoring of Temperature during Sleep: Can We Detect Awareness and Arousal?
Documentation of Potentially Harmful Cerebral Hyperthermia with a Noninvasive Surface Sensor
Noninvasive Quantification over a Brain Temperature Tunnel of Increased Brain Temperature During ECT
The Brain Temperature Tunnel: More Than a Path for Monitoring Temperature
Repeated Comparisons of Brain Tunnel And Sublingual Temperature Measurements
Noninvasive Quantification of Pain Observed via Increased Brain Temperature During Brain Temperature Tunnel Monitoring
Noninvasive Delineation of Ipsilateral Decline in Brain Temperature During Acute Ischemic Stroke
Noninvasive Monitoring of Decrease in Brain Temperature During Monitored Anesthesia Care with Propofol
Monitoring Temperature of the Brain Thermal Tunnel: Is It Influenced by Facial Temperature?
Do Seizures, Pain, Thought and Emotion Share Common Range of Brain Temperature?
Success stories
Patients treated at the BTT Medical Institute
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